Cell Culture Optimization Using an Agilent Bio-Monolith Protein A Column and LC/MS Authors
نویسندگان
چکیده
This application note describes how the Agilent Bio-Monolith Protein A column was applied to the optimization of Chinese hamster ovary cell-culture conditions to produce a recombinant monoclonal antibody with desired structural characteristics, focusing on glycosylation. The workflow demonstrates the versatility and wide applicability of the column in biopharmaceutical and biosimilar development.
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